Zonulin independently contributes to loosening the junctions between cells in the gut. Add together the inflammation and the zonulin, and wheat has a powerful effect on gut permeability, which is really a problem. Again, this is totally separate from the problem of gluten. Included in that stuff is…gluten! Specifically, gliadin, which is a component of gluten. Molecular mimicry works like this: some foreign thing gets into the bloodstream.
The immune system forms antibodies against it. Molecular mimicry may be the reason why people with celiac disease mount an attack on their own gut cells : to your immune system, gliadin looks a lot like the cells lining the gut. The common factor here might be the gluten. In this study , feeding mice a gluten-free diet reduced the rate of Type 1 diabetes in their children. Hey, by the way, guess what other common health problems have an autoimmune component? Obesity and Type 2 Diabetes.
If you thought non-celiac gluten sensitivity was unrelated to autoimmune disease, you thought wrong! This study found that a lot of people with non-celiac gluten sensitivity have autoimmune markers in their blood , suggesting that the wheat exposure might be causing autoimmune issues even without celiac disease. Like with any other major change you make to what you're putting in your body, there could be side effects.
Here are some things you might want to prep for. A lot of the whole-grain foods you cut out on a gluten-free diet like bread and pasta are good sources of fiber. If you simply ditch them without compensating for the loss in other areas of your diet, your digestive system could get all out of wack — which is what you were trying to avoid.
By upping your intake of leafy greens and legumes, you'll avoid this issue. Many people with gluten-sensitivity feel so sick after eating bread products, their appetite suffers for the rest of the day. When you remove it from your diet, you might notice yourself getting hungrier, both because you're appetite's back and because of the food swaps you're making. Vegetable noodles just aren't as filling as the real thing. Those who suffer from "brain fog" describe it as feeling lethargic and generally out of it, and often, it's related to diet.
Gluten intolerance is a fairly common concern. There are several potential causes of gluten intolerance, including celiac disease, non-celiac gluten sensitivity, and wheat allergy 1. All three forms of gluten intolerance can cause widespread symptoms, many of which have nothing to do with digestion. It can cause a wide range of symptoms, including skin problems, gastrointestinal issues, mood changes, and more.
Individuals with celiac disease experience inflammation in the small intestine after eating gluten. This damages the gut lining and leads to poor nutrient absorption, resulting in significant digestive discomfort and frequent diarrhea or constipation 3. Frequent diarrhea can cause some major health concerns, such as loss of electrolytes, dehydration, and fatigue 4. Plus, individuals with celiac disease may experience pale and foul-smelling feces, due to poor nutrient absorption 5.
Feeling tired is a common occurrence among people with autoimmune disorders, including celiac disease 6. Several factors are thought to contribute to fatigue in individuals with celiac disease, including 6 :. This can cause several serious side effects, including decreased energy levels and fatigue 8. A blistering skin condition called dermatitis herpetiformis is one manifestation of celiac disease 9.
Although everyone who has celiac disease is sensitive to gluten, some people with the condition do not experience digestive symptoms that indicate celiac disease Furthermore, several other skin conditions have shown improvement while on a gluten-free diet. These include:. The symptoms, which often involve feelings of hopelessness and sadness, can have a major effect on daily life People with digestive issues seem to be more prone to both anxiety and depression than individuals without any underlying conditions Depression and anxiety are especially common among people who have celiac disease 18 , 19 , An unexpected weight change is often a cause for concern.
Although it can stem from various reasons, unexplained weight loss is a common side effect of undiagnosed celiac disease In one older study in celiac disease patients, two-thirds had lost weight in the 6 months leading up to their diagnosis The weight loss may be explained by a variety of digestive symptoms coupled with poor nutrient absorption.
Iron deficiency causes symptoms such as 27 :. In celiac disease, nutrient absorption in the small intestine is impaired. This results in a reduced amount of iron being absorbed from food 7. Your doctor might recommend trying a gluten-free diet to see if you do have a gluten intolerance.
Keep in mind that other conditions, such as celiac disease and wheat allergies, can cause similar symptoms.
If eliminating gluten from your diet eases your symptoms, this usually indicates gluten intolerance. Your doctor can test for wheat allergies or celiac disease if needed. Excessive gas can be a sign of gluten intolerance.
Other digestive problems, such as bloating, can also occur. If you have a gluten sensitivity, you might begin to have symptoms shortly after eating. For some people, symptoms start a few hours after eating. For others, symptoms can start up to a day after having food with gluten in it.
Gluten intolerance can cause a wide range of symptoms.
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