As an alkalizing agent, LR also helps reduce the levels of acidity within the body. Therefore, doctors may use the solution to treat high acid levels resulting from sepsis or other conditions. LR and saline differ in terms of their chemical content and their overall effects on the body. LR does not last as long in the body, so it is less likely to cause fluid overload, known as hypervolemia.
In addition, it is formulated with sodium lactate to promote the metabolization of bicarbonate, thereby lowering acidity in the body. A study involving people who had undergone colorectal or orthopedic surgery investigated the difference in outcomes between people receiving LR and those getting the equivalent volume of saline solution. The researchers found no statistically significant difference between the two groups for any of the variables that they measured.
These included:. Although both LR and saline are equally effective in most clinical settings, research suggests that LR might be more effective for trauma patients experiencing burns or excessive blood loss. Medical professionals may administer LR in a hospital setting to treat dehydration and restore fluid balance in the body. A doctor will sometimes select LR over traditional saline because it does not remain in the body for as long and is less likely to result in hypervolemia.
Doctors will not typically administer LR for people undergoing blood transfusions , as it can interact with certain blood medications to increase the risk of clotting. If a doctor does decide to administer the two treatments, they will administer each one through a separate IV line. LR is an IV medication, meaning that a doctor or trained nurse will administer it into a vein.
The fluid will pass from an external IV bag, through an IV line, and into the bloodstream. IV fluid regulation refers to the monitoring and control of how much fluid passes from the bag into the bloodstream. Medical professionals may administer LR in one of two ways : manually or via an electric pump. With the manual technique, a healthcare professional adjusts the pressure of the clamp on the IV tube to reduce or facilitate the flow rate.
They may also count the number of drops per minute to ensure an accurate and safe flow. With the electric pump method, a healthcare professional programs an electric pump to deliver the correct dosage of LR automatically. According to the Food and Drug Administration FDA , many of the reported problems with fluid infusion are due to electric pump use.
For instance, these devices can be faulty, or software or electrical issues can occur. Side effects due to LR are rare, and those that do occur are more commonly the result of an intolerance or allergic reaction to the solution.
Some rare side effects, which occur at the injection site, include:. The body metabolizes this component to something called bicarbonate. Also, normal saline has a higher chloride content.
This can sometimes cause renal vasoconstriction, affecting blood flow to the kidneys. Pharmacies instead mix normal saline with the following IV solutions:. The extra calcium could bind with the preservatives added to blood by blood banks for storage.
This potentially increases the risk of blood clots. According to B. Some of the reasons why a person may get this IV solution include:. It can therefore be used to wash out a wound. It can also be used during surgery to irrigate the bladder or a surgical site. This helps to wash away bacteria or make a surgical site easier to see.
When the solution goes into the vein, it goes inside cells as well as outside. Ideally, the solution helps to maintain or achieve fluid balance in your body. These conditions include:. This includes sodium and potassium. Some lactated ringers solutions include dextrose, a type of glucose. Allergic reactions may occur in people who have corn allergies. A doctor will consider factors such as your age, how much you weigh, your overall health, and how hydrated you already are.
For these medications, a normal saline solution is safer. Sign up for our Health Tip of the Day newsletter, and receive daily tips that will help you live your healthiest life. Singh S, Davis D. Ringer's lactate. In: StatPearls. Updated March 22, A critical appraisal of intravenous fluids: from the physiological basis to clinical evidence.
Nephrol Dial Transplant. Effect of lactate versus acetate-based intravenous fluids on acid-base balance in patients undergoing free flap reconstructive surgeries. J Anaesthesiol Clin Pharmacol. Galvango SM. Your Privacy Rights. To change or withdraw your consent choices for VerywellHealth. At any time, you can update your settings through the "EU Privacy" link at the bottom of any page.
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